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Care should be taken when removing plugs so as not to cause irritation to the tissues. They can be seen as firm white creamy colored material often protruding at the tip of the penis. Clinical Signs May observe the following: Firm, cream colored material at tip of penis A perceptible odor may or may not be present Etiology The spontaneous formation of vesical proteinaceous plugs, otherwise commonly referred to as penile or penis plug, is frequently seen in the aging male rat. In addition secretions called smegma, composed of oils, moisture, and shed epithelial cells help to keep the glans moisturized. Prevention While there is no prevention to the formation of proteinaceous plugs assisting the elderly or ill rat by gently removing these plugs can help to prevent inflammation to the urethra, as well as, infection and discomfort. Carefully massage to project penis outward from the sheath to remove the plug.

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Averi. Age: 29.
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Prevention While there is no prevention to the formation of proteinaceous plugs assisting the elderly or ill rat by gently removing these plugs can help to prevent inflammation to the urethra, as well as, infection and discomfort.

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Amelia. Age: 28.
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In addition secretions called smegma, composed of oils, moisture, and shed epithelial cells help to keep the glans moisturized. Carefully massage to project penis outward from the sheath to remove the plug. In male rats where an orchiectomy neuter has been performed the development of urethral plugs is significantly decreased Bennett, Soft Tissue Surgery, , p.

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